My lab is interested in how the intestine develops. We examine how this development can can disrupted on a cellular level and how these changes can lead to a loss of intestinal continuity using an intestinal atresia mouse model (an Fgfr2IIIb-/- model). We also investigate the role of the extracellular matrix in guiding the development of specific subregions of small intestine.
Zaremba KM, Reeder AL, Kowalkowski A, Girma E, Nichol PF. “Utility and limits of Hprt-Cre technology in generating mutant mouse embryos.” Journal of Surgical Research. 2014 Apr;187(2):386-93. Epub 2013 Oct 29.
Reeder AL, Zaremba KM, Liebl RM, Kowalkowski A, Nichol PF. “Exogenous Sonic hedgehog protein does not rescue cultured intestine from atresia formation.” Journal of Surgical Research. 2014 Mar;187(1):14-8. Epub 2013 Dec 7.
Smith PH, Bartlett EL, Kowalkowski A. “Cortical and collicular inputs to cells in the rat paralaminar thalamic nuclei adjacent to the medial geniculate body.” Journal of Neurophysiology. (2007): 98:681-95
Smith PH, Bartlett EL, Kowalkowski A. “Unique combination of anatomy and physiology in cells of the rat paralaminar thalamic nuclei adjacent to the medial geniculate body.” Journal of Comparative Neurology.(2006): 496:314-34