The Chapman lab has several interests related to the mechanisms involved with membrane fusion, synaptic transmission, and synaptic plasticity:
- Relating basic synaptic properties to aspects of network-level function and plasticity
- Elucidation of the receptors, entry pathways, and the molecular basis for translocation across membranes, of Botulinum (BoNT) and Tetanus neurotoxins (TeNT)
- Molecular mechanisms regulating organelle distribution and homeostasis in mammalian neurons
- Role of synaptotagmins in hormone secretion in the pituitary